Small clinical trial finds cannabinoid formulation reduced morphine use by 48%

A randomized trial of 69 emergency-department patients found a single sublingual dose containing 19.8 milligrams each of THC and CBD plus terpenes reduced 24-hour morphine use from 33.2 to 17.4 milligrams without higher reported pain. The small study, which disclosed supplier employment ties and three temporary hallucinations, gives Oklahoma medical product developers a clinical signal that still needs larger independent replication.